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Pekka Jäkälä

Curriculum vitae

Career:
Research assistant and researcher, Department of Neurology, University of Kuopio, 1989-­1994
Assistant physician, Department of Neurology, University Hospital of Kuopio, 1995-­2002
Senior physician of the ward (Head of Inpatient Clinic), Department of Neurology, University Hospital of Kuopio, 2003-2006
Senior physician of the ward (Head of Outpatient Clinic), Department of Neurology, University Hospital of Kuopio, 2007-2009
Head of Stroke Unit (Neurological Care Unit), University Hospital of Kuopio, 2004-1.6.2009
Director, The Finnish Brain Research and Rehabilitation Center Neuron, 1.6.2009‑31.7.2012
Consultant, Department of Neurology, University Hospital of Kuopio, 2009-­1.6.2012
Director, NeuroCenter, University Hospital of Kuopio 1.8.2012-­
Chief Physician, Department of Neurology/NeuroCenter, University Hospital of Kuopio 1.8.2012-

Good Clinical Practice (GCP)-­related activities:
Memory Research Clinic, University of Kuopio, Investigator in drug treatment trials of Alzheimer ́s disease, 1995‑1997
Investigator in several drug treatment trials in acute stroke and secondary prevention (e.g. FAST, Abestt II, Repinotan, ECASS III, DIAS-­2, Profess, Tra2P-­TIMI50, Rocket, Perform, Engage, ImpACT‑24, ALIAS Part2 etc.), 2002-­ongoing
Updated GCP examination 2011  
Principal Investigator of Kuopio University Hospital and University in Stroke Trials:
ECASS III, Tra2P‑TIMI50, Rocket, Perform, ImpACT‑24, ALIAS Part2    

Education:  
Matriculation examination  (Secondary School Graduation), Tiirismaa Lahti, 1986.
Medical student, University of Kuopio, Finland, 1987.
Bachelor of medicine, University of Kuopio, 1989.
Academic dissertation, University of Kuopio, 1992.  
M.D., University of Kuopio, 1994.
Certified physician, 1994.
Ph.D., University of Kuopio, 1995.
Certified neurologist, 2003.  

Doctoral examination:
PhD in medicine, University of Kuopio, examined 17th December 1992: Modulation of attention and working memory by noradrenergic, serotonergic and cholinergic systems -­ An experimental neuropsychopharmacological study. Series of Reports, No. 26. University of Kuopio, Department of Neurology, Kuopio, Finland, 1992.

Adjunct professorships, Docents:
Docent of experimental neurology, University of Kuopio, 1997.  
Docent of neurology, University of Kuopio, 2006.

Professorships:
Professor of neurodegenerative diseases and rehabilitation, University of Eastern Finland (previous University of Kuopio), 2009-2012.
Acting professor of neurology, University of Eastern Finland, 1.8.2012-­

Post-­graduate studies and studies abroad:  
Junior research fellow, Academy of Finland, 1995-­1998.
Visiting scientist, Center for Molecular Biology (ZMBH), University of Heidelberg, Germany, research group of Professor Konrad Beyreuther, 1997-1999.

Leadership education:
”Sinustako vuosituhannen johtaja”- koulutus 25 op, 2006.
Director, The Finnish Brain Research and Rehabilitation Center Neuron, 2009-­31.7.2012.
eMBA education 1.1.2013 – ongoing (100 op).
 
Linguistic abilities:
Finnish (native), English (fluent), German (fluent), Swedish (fluent, official Swedish examination in 1994).
   
Academy of Finland:  
Junior Research Fellow, Academy of Finland, 1995‑1998. 
Visiting Scientist, Center for Molecular Biology (ZMBH), University of Heidelberg, Germany, research group of Professor Konrad Beyreuther with Academy funding, 1997-­1999.  
Research funding from the Academy of Finland for α‑synuclein transgenic mice model of Parkinson's disease and Dementia with Lewy bodies, 2003-2005.  

Supervised Pro-­Gradu Dissertations of Medical Students:  
Tarja Puumala (8.10.1993, University of Kuopio)
Sirja Ruotsalainen (12.1.1997, University of Kuopio)
Jarmo Kaukua (30.5.1997, University of Kuopio)
Markus Björklund (23.8.2000, University of Kuopio)
Selja Vaalto (12.12.2005, University of Kuopio)
Ossi Nerg (5.12.2006, University of Kuopio)
Anna‑Maija Saarinen (ex-­Voutilainen) (16.12.2008, University of Kuopio)
Tomi Timonen (23.4.2010, University of Eastern Finland)
Antti Muuronen (2013, University of Eastern Finland)
Ida Paust (2013, University of Eastern Finland)
Mikko Taina (2013, University of Eastern Finland)
Alexandra Kulmalahti (2013, University of Eastern Finland)
Sampo Kilpiäinen (2014, University of Eastern Finland)
Laura Värri (during 2014, University of Eastern Finland)  
 
Supervised Doctoral (Ph.D) Dissertations:   
Jukka Puoliväli (An experimental study on the cholinergic modulation of cortical arousal and cognitive functions, 17.11.2001, University of Kuopio)  
Jun Wang (The role of Ab-­peptide on spatial memory, EEG, auditory evoked potentials and nicotinic cholinergic receptors in A/P transgenic mice, 20.3.2003 University Of Kuopio)  
Anu Lipsanen (Thalamus pathology in stroke, 4.4.2014, University of Eastern Finland)
Mitkari Bhimashankar (Intra-­arterial delivery of human bone marrow mesenchymal stem cells in rats with cerebral ischemia, 29.5.2015, University of Eastern Finland)
Tuuli Miettinen (Neuroresources – the use of resources in the acute treatment of stroke and cost‑effectiveness of the treatment, estimated defending of the thesis during 2018)  

Opponent in Ph.D Thesis Examination: 
Nina Kemppainen (Brain Dopamine Transporter and Receptors in Alzheimer's Disease, 20.9.2002, University of Turku)  
Susanna Melkas (Poststroke survival and ischemic stroke recurrence: the cerebral small-­vessel disease perspective, 18.11.2011, University of Helsinki)  

Statements on Academic Examinations:  
Ari Miettinen, Pro-­Gradu dissertation (16.3.1998, University of Kuopio)
Heikki Numminen, Adjunct Professorship/Docent (2008, University of Tampere)
Atte Meretoja, Ph.D. Thesis Examination (2011, University of Helsinki)
Mika Martikainen, Ph.D. Thesis Examination (2011, University of Turku)  
Tiina Metso, Ph.D. Thesis Examination (2012, University of Helsinki)
Daniel Strbian, Adjunct Professorship/Docent (2012, University of Helsinki)
Atte Meretoja, Adjunct Professorship/Docent (2012, University of Helsinki)    
 
Scientific cooperation and the diffusion of knowledge:
Cerebrovascular Disorders and Stroke Research in University of Eastern Finland (Kuopio Campus):
http://www.uef.fi/neuro/stroke-director
http://www.uef.fi/neuro/stroke-­group  
Clinical Research led by Jäkälä  

Collaborators:
Experimental Stroke Research: Jukka Jolkkonen, Research Director, University of Eastern Finland
Clinical Neurorehabilitation: Dr. Kauko Pitkänen, The Finnish Brain Research and Rehabilitation Center Neuron, Kuopio, Finland; Dr. Sinikka Peurala, PT, PhD, The Finnish Centre for Interdisciplinary Gerontology, Faculty of Sport and Health Sciences, University of Jyväskylä, Finland; Prof. Juha Kinnunen, Prof. Olli‑Pekka Ryynänen and Dr. Markku Hänninen, The Kuopio Welfare Research Center KWRC, UEF; Prof. Pasi Karjalainen, Department of Physics and Mathematics, UEF  
Mechanisms and Imaging of Stroke: Dr. Petri Sipola, Department of Radiology, Kuopio University Hospital; Prof. Ritva Vanninen, Department of Radiology, Kuopio University Hospital; Dr. Marja Hedman, Department of Cardiology, Kuopio University Hospital; Prof. Hannu Manninen, Department of Radiology, Kuopio University Hospital; Prof. Esa Mervaala, Department of Neurophysiology, Kuopio University Hospital  
Cost‑effectiveness of invasive stroke treatments: Prof. Esko Ruokonen and Assoc. prof. Stepani Bendel, Department of Intensive Care Unit, Kuopio University Hospital  

Publications:  
Over 70 scientific publications in peer reviewed international journals on stroke and other neurological disorders, several book chapters.